ADENOSINE TRIPHOSPHATE IN MAGNESIUM ANESTHESIA
نویسندگان
چکیده
منابع مشابه
Nonparallel isometric tension response of rabbit soleus skinned muscle fibers to magnesium adenosine triphosphate and magnesium inosine triphosphate
The isometric tension response of single "skinned' rabbit soleus muscle fibers to MgATP and McITP in the absence of calcium was studied. [MgATP] or [MgITP] was varied in solutions of ionic strength 0.30 and temperature 20 degrees C. Steady-state tension that developed in MgATP or MgITP solutions was a biphasic bell-shaped function of log [MgATP] or log [MgITP] which increased from zero to maxim...
متن کاملNonparallel Isometric Tension Response of Rabbit Soleus Skinned Muscle Fibers to Magnesium Adenosine Triphosphate and Magnesium Inosine Triphosphate
It has long been accepted that M g A T P is the energy source for contraction. Evidence has also accumulated indicating that M g A T P plays an important role in the regulation of contraction (Weber and Murray, 1973; Inoue and Tonomura , 1974; Godt, 1974; Orentlicher et al., 1977). In an a t tempt to better understand the dual role of ATP in contraction, several researchers have studied the eff...
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Factors affecting inhibition of myosin ATPase by ATP, such as concentration of the enzyme, of ATP, and of the divalent metals, calcium and magnesium, have been studied and the results are reported here. Experiments were carried out under conditions in which no known magnesium effects occurred, so that only the effect of calcium on the nucleoside triphosphatase activity of myosin A could be qual...
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The kinetics of protein-fluorescence change when rabbit skeletal myosin subfragment 1 is mixed with ATP or adenosine 5'-(3-thiotriphosphate) in the presence of Mg(2+) are incompatible with a simple bimolecular association process. A substrate-induced conformation change with DeltaG(0)<-24kJ.mol(-1) (i.e. DeltaG(0) could be more negative) at pH8 and 21 degrees C is proposed as the additional ste...
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The regulation of ATP metabolism by inorganic phosphate (Pi) was examined in five normal volunteers through measurements of ATP degradation during relative Pi depletion and repletion states. Relative Pi depletion was achieved through dietary restriction and phosphate binders, whereas a Pi-repleted state was produced by oral Pi supplementation. ATP was radioactively labeled by the infusion of 18...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1943
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)72368-5